The Qian Lab

California Institute of Technology


Experimental work

[1] A cargo-sorting DNA robot. Anupama J. Thubagere, Wei Li, Robert F. Johnson, Zibo Chen, Shayan Doroudi, Yae Lim Lee, Gregory Izatt, Sarah Wittman, Niranjan Srinivas, Damien Woods, Erik Winfree, and Lulu Qian. Science, 10.1126/science.aan6558, 2017. (pdf) (supp info)

Perspective: "DNA robots sort as they walk" by John H. Reif, 10.1126/science.aao5125, 2017.

Caltech news story    Media coverage

 

 

 

 

 

[2] Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components. Anupama J. Thubagere, Chris Thachuk, Joseph Berleant, Robert F. Johnson, Diana A. Ardelean, Kevin M. Cherry, and Lulu Qian. Nature Communications, 10.1038/ncomms14373, 2017. (pdf) (supp info)

Caltech news story

[3] Programmable disorder in random DNA tilings. Grigory Tikhomirov, Philip Petersen, and Lulu Qian. Nature Nanotechnology, 10.1038/nnano.2016.256, 2016. (pdf) (supp info)

In the Classroom: "Programming random mazes" by Philip Petersen, 10.1038/nnano.2017.30, 2017. (pdf)

News and Views: "DNA origami tiles: Nanoscale mazes" by Fei Zhang, Fan Hong and Hao Yan, 10.1038/nnano.2016.263, 2016. (pdf)

Caltech news story

 

 

 

 

 

[4] Neural network computation with DNA strand displacement cascades. Lulu Qian, Erik Winfree, and Jehoshua Bruck. Nature, 475:368-372, 2011. (pdf) (supp info)

News and Views: "DNA and the brain" by Anne Condon, 475:304-305, 2011. (pdf)

Media coverage     Youtube video

[5] Scaling up digital circuit computation with DNA strand displacement cascades. Lulu Qian and Erik Winfree. Science, 332:1196-1201, 2011. (pdf) (supp info)

Perspective: "Scaling up DNA computation" by John Reif, 332:1156-1167, 2011. (pdf)

News and Views: "DNA computes a square root" by Yaakov Benenson, Nature Nanotechnology, 6:465-467, 2011. (pdf)

Media coverage     Youtube video

Theoretical work

[1] Parallel and Scalable Computation and Spatial Dynamics with DNA-Based Chemical Reaction Networks on a Surface. Lulu Qian and Erik Winfree. In S. Murata and S. Kobayashi, editors, DNA Computing and Molecular Programming, LNCS 8727:114-131, 2014. (pdf)

[2] Efficient Turing-universal computation with DNA polymers. Lulu Qian, David Soloveichik, and Erik Winfree. In Y. Sakakibara and Y. Mi, editors, DNA Computing and Molecular Programming, LNCS 6518:123-140, 2011. (pdf)

[3] A simple DNA gate motif for synthesizing large-scale circuits. Lulu Qian and Erik Winfree. Journal of the Royal Society Interface, 8:1281-1297, 2011. (pdf) Conference version in A. Goel, F. C. Simmel and P. Sosik, editors, DNA Computing and Molecular Programming, LNCS 5347:70-89, 2009. (pdf)