The Qian Lab

California Institute of Technology


Experimental work

[1] Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components. Anupama J. Thubagere, Chris Thachuk, Joseph Berleant, Robert F. Johnson, Diana A. Ardelean, Kevin M. Cherry, and Lulu Qian. Nature Communications, 10.1038/ncomms14373, 2017. (pdf) (supp info)

Caltech news story

[2] Programmable disorder in random DNA tilings. Grigory Tikhomirov, Philip Petersen, and Lulu Qian. Nature Nanotechnology, 10.1038/nnano.2016.256, 2016. (pdf) (supp info)

In the Classroom: "Programming random mazes" by Philip Petersen, 10.1038/nnano.2017.30, 2017. (pdf)

News and Views: "DNA origami tiles: Nanoscale mazes" by Fei Zhang, Fan Hong and Hao Yan, 10.1038/nnano.2016.263, 2016. (pdf)

Caltech news story

 

 

 

 

 

[3] Neural network computation with DNA strand displacement cascades. Lulu Qian, Erik Winfree, and Jehoshua Bruck. Nature, 475:368-372, 2011. (pdf) (supp info)

News and Views: "DNA and the brain" by Anne Condon, 475:304-305, 2011. (pdf)

Media coverage     Youtube video

[4] Scaling up digital circuit computation with DNA strand displacement cascades. Lulu Qian and Erik Winfree. Science, 332:1196-1201, 2011. (pdf) (supp info)

Perspective: "Scaling up DNA computation" by John Reif, 332:1156-1167, 2011. (pdf)

News and Views: "DNA computes a square root" by Yaakov Benenson, Nature Nanotechnology, 6:465-467, 2011. (pdf)

Media coverage     Youtube video

Theoretical work

[1] Parallel and Scalable Computation and Spatial Dynamics with DNA-Based Chemical Reaction Networks on a Surface. Lulu Qian and Erik Winfree. In S. Murata and S. Kobayashi, editors, DNA Computing and Molecular Programming, LNCS 8727:114-131, 2014. (pdf)

[2] Efficient Turing-universal computation with DNA polymers. Lulu Qian, David Soloveichik, and Erik Winfree. In Y. Sakakibara and Y. Mi, editors, DNA Computing and Molecular Programming, LNCS 6518:123-140, 2011. (pdf)

[3] A simple DNA gate motif for synthesizing large-scale circuits. Lulu Qian and Erik Winfree. Journal of the Royal Society Interface, 8:1281-1297, 2011. (pdf) Conference version in A. Goel, F. C. Simmel and P. Sosik, editors, DNA Computing and Molecular Programming, LNCS 5347:70-89, 2009. (pdf)